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Abstract #0647

Oxygen Enhanced Lung MRI by Simultaneous Measurement of T1 and T2* During Free Breathing

Simon Triphan1, 2, Felix A. Breuer1, Hans-Ulrich Kauczor2, Peter M. Jakob1, 3

1Research Centre Magnetic Resonance Bavaria e.V., Wrzburg, Bayern, Germany; 2Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Baden-Wrttemberg, Germany; 3Experimental Physics 5, University Wrzburg, Wrzburg, Bayern, Germany

While both T1 and T2* are reduced in hyperoxic conditions, these changes reflect different aspects of lung function. A method for measuring both parameters simultaneously using a inversion recovery multi-gradient echo experiment is proposed. By applying an asymmetric radial readout with a golden angle distribution, lung signal is maximised while enabling self-gating to compensate for breathing motion. Since the dc-signal is distorted by the inversion recovery, a correction to recover an undisturbed signal is shown. Generating self-gated parameter maps provides co-registration for T1 and T2* maps as well as for maps acquired under different oxygenation conditions.

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Keywords

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