High-Resolution UTE MRI Longitudinal Non-Invasive Characterization of a Mouse Model of Chronic Asthma: From Inflammation to Bronchial Remodeling Assessment

Keywords

absence according acquisition action administrations airways already animals antigen appropriate assess assessment asthma asthmatic axial body breathing bronchial bronchus brown built characterization characterized chosen chronic circulating clarify clinical complex computed consistent constantly control controls correlates cover culminate curie custom cycle days delineated described disease drawn drug equivalent even evolution experimental experimentation exploiting extended extending facial feasibility frequent fully functional help histological house human identifying immediate increasing index indicated inflammation inflammatory injection injections intensity interruption intranasal invasive just knowledge longitudinally lumen lung manually mass material measure measured mechanism mice microscopic mild minutes mixture model motion mouse muscle needed negligible place placed plastic previous procedure process protocol proton radiology radius received regressive remodeling required residual resolution reversible ring saline sections seems segmentation shaped side significantly similarly since slice slow software solution stained statistical studied studies take technologies temperature third though together transmitter triggers typical ultra undergo vessels volume volumes warm weeks whole zoom