Meeting Banner
Abstract #0573

Feasibility of MRI Attenuation Correction in Cardiac-Gated FDG-PET

Jeffrey MC Lau1, Richard Laforest2, Shivak Sharma1, Jonathan McConathy2, Agus Priatna2, 3, Luciano Amado1, Robert J. Gropler2, Pamela K. Woodard2

1Cardiology, Washington University in St. Louis, Saint Louis, MO, United States; 2Radiology, Washington University in St. Louis, Saint Louis, MO, United States; 3Siemens Medical Solutions, Malvern, PA, United States

The objective of this study is to determine the reproducibility of myocardial specific uptake values (SUVs) obtained in EKG-gated and non-EKG-gated cardiac 18F-FDG PET imaging using an MR attenuation correction (AC) &[mu] -map instead of CT. In non-EKG-gated PET-CT and PET-MR, there is excellent per patient correlation between the SUVs (R2 =0.97). In EKG-gated PET-MR, SUVs vary over the cardiac cycle, with higher SUV at end-systole and lower SUV at end-systole. Our findings show that, despite the marked differences in AC methods, myocardial PET SUVs measured using MR-AC show excellent correlation to myocardial SUVs obtained by standard PET-CT imaging.

Keywords

abdominal accurate acquisition activity additional although among anatomic anterior approved approximating arms assessment attenuation available axis background biograph body brain cardiac cardiology care challenge clinically comparable computer correction correlation creation cross cycle density derived despite determine diagnostic diastole directly dividing dose dotted dual early electron entire estimation evaluation excellent feasibility filter findings full functional furthermore gated gating generates glucose heart highly history impact incorporate injected instead iterations known lesions likelihood list long magma marked maximization measure measured medical metabolic metabolism minutes mode muscle myocardial myocardium need objective offers opposed organs papillary partial patient patients phenomenon phys pilot post posterior potential prior radiology reconstructed reconstruction regarding remained reproducibility researchers resolution respectively retrospectively saint scar secondary section segmentation segments separates series short significantly simultaneous soft software solid solutions specifically statistically subset subsets superimposed systems systole technology tissue tracing true underwent unexplored unlike uptake variable variation vary ventricular vibe volume water whole