Meeting Banner
Abstract #0543

Off-Resonance-Robust Velocity-Selective Magnetization Preparation for Non-Contrast-Enhanced Peripheral MRA

Taehoon Shin1, Bob S. Hu1, 2, Dwight G. Nishimura1

1Electrical Engineering, Stanford University, Stanford, CA, United States; 2Palo Alto Foundation, Palo Alto, CA, United States

Velocity-selective (VS) excitation is a promising magnetization preparation for non-contrast-enhanced (NCE) MRA as it can generate positive angiographic contrast directly without subtraction. This work aims to develop a new version of the VS excitation pulse sequence that is robust to off-resonance and demonstrate its application to NCE peripheral MRA. The proposed VS pulse design modifies a reference k-space-based design by incorporating 180° refocusing pulses and tailoring sequence parameters in a limited velocity region-of-interest. The improved off-resonance immunity and clinical feasibility of NCE peripheral MRA using the proposed VS preparation are shown in healthy and patient subjects.

Abstract PDF Presentation Video

Keywords

ability according aimed alto amount angiography application applying arrows arteries artery audience background balanced band bands bars beats bipolar bottom bound calves cardiac carotid channel circles clinical coil compensate composite consisted contains contrast coronal create delay dependence design designed designs develop diagram directly done electrical engineering enhanced entire errors even examination excitation feasibility femoral field flow formalism foundation gated generate gradient gradients healthy heart identified immunity imperfect improved inhomogeneity inserted made magnetization mild modifications modified moment much narrowing numerically occlusion original pass patient peak peripheral physicists positive potential preparation preparations presence press profile promising proportion proportional proposed pulse pulses radiologists readout reduced reformatted reliably resolution respectively robust rotation rotations rules saturation scaling scanning scheduled segment selective shin simulated slice space spatial split subject subsequent subtraction subtractive suffers suppression system systolic tailoring target thighs train uniform unipolar upper variability vascular velocity view volunteers white