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Abstract #0311

Motion Robust High Resolution FLASH

Onur Afacan1, Ali Gholipour1, Erez Nevo2, Simon K. Warfield1

1Computational Radiology Laboratory, Department of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, United States; 2Robin Medical, Inc, Baltimore, MD, United States

In this work we propose a novel motion robust high-resolution FLASH acquisition scheme to be used for cortical lesion detection in uncooperative subjects. This scheme is based on acquiring multiple low-resolution images with different orientations and then combining these acquisitions into an isotropic high-resolution image using super-resolution reconstruction. We use a motion sensor to identify the low-resolution images corrupted with motion to reacquire them, as well as to correct for the motion between the low-resolution acquisitions. With this method whole brain images with isotropic resolution of 0.6 mm were reconstructed with a total scan time of 20 minutes.

Keywords

able accuracy accurate acquiring acquisition acquisitions adult applied assumption axes bandwidth black blue brain built channel children coil combining computational consist consisting correct correction corrupted cortical cover coverage datasets degrees detect detected detection distorted domain double electromagnetic enforce even field flash forty function good gradient green head healthy hospital identify implementation improved infeasible inverse inversion isotropic journal laboratory lesions likelihood long maintaining makes match matrix medical medicine middle minutes motion move moved movement neurology novel oblique occurrence orientation orientations orthogonal output particular patient personnel pipe predefined previous problem processing profile propose proposed quality radiology reacquire reacquisition readout recent reconstruct reconstructed reconstruction reconstructions recovery reduce reported representation resolution robin robust sample sampling scanned scanner scheme school sensor sensors shorter shot slab slabs slice slices solve space spherical spoiled stay still strategy strengths studies subjects substantial super support technical thank threshold tracking trans transformed trio twenty uncooperative uniform volunteer volunteers whole