EGFR MAb-Bioconjugated Superparamagnetic Iron Oxide Nanoparticles as a Specific MRI Contrast Agent for Detection of Brain Glioma in vivo

Keywords

accumulation administration agent allow although anatomy animal antibody applicability application applications assays assessment attractive bearing become better blood blue brain cancer cancers carotid cells cellular chemotherapy china clinical coil college concentrations conjugated considerable contrast define delivery depict designed despite detection developed developing diagnosis discovery documented earlier efficiently elucidate enhanced enhancement exertion exhibited findings fourthly good histochemical hospital human hydrodynamic important improve improvement in vivo injection insert intra iron label linked magnetization materials medical medicine model molecule monitoring monoclonal need negative noninvasive offers oxide particle picture poor postoperative potentially preferential processes produce profile prognosis prolonged promising property radiation radiotherapy rapid rats real receptor recurrent regulates relatively remarkable resection retention sacrificed safer saturation scanner scanning science secondly section sections selectively sensitivity side significantly specially specifically specificity stained strategies strategy strong subsequent suggested suitable surgical system target targeted targeting technology therapy thirdly tissue tool toxicity translated treated tumor tumors undesired upper useful valuable various vitro widely