Serial Proton MR Spectroscopy of Gray and White Matter in Relapsing-Remitting Multiple Sclerosis

Keywords

abnormalities absence accounted annals annually arrowhead audience axial brain characterize chemical choline clinically coefficients cohort concentrations contrast controls corpus correlate correlations cortex criteria criterion cross dashed decreasing deep defined definite described despite diagnostic diffuse disability distributions divided done dotted duration dysfunction expanded field finally fitted flair fluid focal fractions frequent functions global gray guidance guided guidelines healthy hour house increasing indicated injury inter intervals intra investigated involvement knowledge larger lesion linear load longitudinal magnitude mask masks matched median metabolism metabolite metabolites metrics minutes model neurologists neurology nuclei oded orange overlaid panel partial patient patients phantom post previously prospectively protocol protocols proton quantitative radiology rage random real recovery recruited registered regression relapses relapsing remitting replacement represents role scale scanned sclerosis scores sectional segmentation semi serial significantly slices software solid spectra spectroscopic spectroscopy spinal statistically status suggesting suggests superimposed target tissue took treatment trend trends variance versus view volume volunteers white women years