1Advanced
Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United
States; 2Harold C. Simmons Cancer Center,, UT Southwestern Medical
Center, Dallas, TX, United States; 3Department of Internal
Medicine, UT Southwestern Medical Center, Dallas, TX, United States; 4Advanced
Imaging Research Center, University of Texas Southwestern Medical Center,
Dallas, TX, United States
We report the first in vivo spectroscopic imaging of 2HG at 7T using an optimized echo-time PRESS-based localization method in subjects with brain tumors. We present phantom and in vivo data and show the elevated 2HG levels in tumor patients. Metabolites concentration maps are also presented.