Meeting Banner
Abstract #0109

Simultaneous Arterial Spin Labelling MRI and H2O15 Position Emission Tomography

Ke Zhang1, Hans Herzog1, Christian Filss1, Thomas Fischer2, Walter Sturm3, Burkhard Brocke2, Nadim Jon Shah1, 4

1Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Forschungszentrum Jlich GmbH, Jlich, Germany; 2Neurobiology of Personality and Neurogenetics, Department of Psychology, Dresden Universi Laboratory, Dresden, Germany; 3Clinical Neurology , University Hospital Aachen, Aachen, Germany; 4Department of Neurology, JARA, RWTH Aachen University, Aachen , Germany

A number of studies have compared ASL-MRI and 15O-water PET for the evaluation of ASL reliability and reproducibility. But none of these studies had the possibility to perform both techniques simultaneously to minimize the physiological variations. In this work, a simultaneous ASL-MRI and 15O-water PET approach has been implemented on a hybrid MR-PET for a truly quantitative comparison between the two methods in absolutely the same physiological and functional status.

Keywords

absolutely acquisition allows angiography applied array arterial arteries artery avalanche avoid axial basic bird blood bore brain calculation carotid cassettes caused channel clinical coil coils comparative compatible continuous copper coupled crystals cyclotron dedicated delay delivers deprivation detector diameter diodes emission employing ensure entry equation explicit field fitting five flight flow flowing form function functional gradient head hybrid individual initial injected injection inner insert integrated inter invert laboratory listed magnetization majority male marked materials matrix medical medicine minimal minimize minutes modalities mode modified module modules neurology newly none optimal optimized orientation outer paired partial perfusion perturbation photo physics physiological placed plotting position possibility pseudo psychology pulses quadratic qualitative quantified quantitative quick ranging readout readouts receive recorded relation reproducibility resolution revealed sampling saturation scale scanner selected shah shielded shot similarity simultaneous simultaneously sleep slices spin started statistical status studies subjects summed tomography tracer train transmit transverse trio variations vertebral view water whole years