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Abstract #4573

Whole-Heart Quantification of Myocardial Perfusion with Spiral Pulse Sequences

Yang Yang1, Sujith Kuruvilla2, Christopher Kramer2, 3, Craig Meyer1, 3, Michael Salerno2, 3

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 2Medicine, University of Virginia, Charlottesville, VA, United States; 3Radiology, University of Virginia, Charlottesville, VA, United States

We demonstrated the successful application of whole ventricular coverage absolute quantitative first-pass myocardial perfusion imaging using accelerated spirals in healthy volunteers. This sequence can acquire 8 short axis slices in 480ms enabling full ventricular coverage at heart rates up to 125 BPM.

Keywords

absolute accelerated acceleration accounted achieve acquisition adding additional additionally advantages application arterial artery artifacts available axis beats biomedical blood calibration capable cardiac channel close coil collected collecting collects concentration conjugate consistency convert coronary cover coverage covering curves dark degrees density determining developed diagnosing differ disease dual effective efficiency eliminating enables enabling engineering expected fashion fidelity finite flow full function gradient growing healthy heart implications important included increasing independent induced injection input instead integrated interleaved interleaves iterative magnetization maps measures medicine middle mode motion myocardial myocardium need noise normalized observer optimal optimized parallel pass patients percentage perfusion permitting pixel previously prior profile proposed prospectively pulse quantification quantitative radiology rather reconstructed reconstruction recovery representative reproducible required resolution rest robustness saturation scanner scanning schematic segment sensing sequential short shot simulation slice slices spiral spirit stress subjects successful sufficient support supporting temporal term tool transform transverse undergoing validation ventricular visually volunteer volunteers whole window yang