Meeting Banner
Abstract #4488

Left Ventricular Function in a Single Breathhold with 3D Radial CINE BSSFP and 3D Through-Time Radial GRAPPA

Kestutis Barkauskas1, Vidya Nadig2, Bruce S. Spottiswoode3, Sven Zuehlsdorff3, Nicole Seiberlich1

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 2Heart and Vascular Center, Metro Health Hospital, Cleveland, OH, United States; 3Cardiovascular MR R&D, Siemens Medical Solutions, Chicago, IL, United States

This work applies 3D Through-time Radial GRAPPA to reconstruct images depicting cardiac motion acquired with an ECG-gated, 3D radial cine bSSFP sequence using an angularly-undersampled stack-of-stars cylindrical trajectory during a single breathhold. A total of 10 repetitions of fully-sampled 3D radial data acquired during free-breathing formed the calibration reference. Bland-Altman analysis of ejection fraction in 10 healthy volunteers showed that differences between the proposed 3D radial approach which required less total scan time and only a single breathhold and a clinical standard 2D segmented cine multi-breathhold acquisition were not statistically significant (mean +/- 1.96*SD of bias: 0.7 +/- 5.5%).

Keywords

acceleration acceptable achieved acquisition additional aliasing alternative angular angularly annual applied approved array audience basic bias biomedical bland blood body breathing calculation calibration cardiac cardiologists cardiovascular central channels cine clinical code collect collected combination complete comprised constrained contours contrast coverage cycle cycles cylindrical depending despite diastole draw dummy duration easier ejection eliminate employ engineering entire equivalent evaluated extract fold fraction free fully function functional gated gold grant gridded health healthy heart heartbeats hospital iterative just lieu limits linear matrix medical metro motion muscles myocardium orientation oversampling papillary parallel participate partition partitions patients period periodic pilot plot presumption projections quality radial radiologists readily reconstruct reconstruction reconstructions recruited reduced relies repetitions representative required reserve resolution respectively scanner segmentation segmented segmenting several shorten shot significance slice slices solid solutions spine stack stars statistically studies subject sufficient symptomatic systole systolic target temporal toolbox trajectory uniform vascular ventricular versus volume volumes volumetric volunteers western whole yield