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Abstract #4285

Respiratory Self-Gating for Free-Breathing Magnetization Transfer MRI of the Abdomen

Weiguo Li1, Ning Jin2, Tianjing Zhang1, Andrew C. Larson1

1Radiology, Northwestern University, Chicago, IL, United States; 2Siemens Healthcare, Columbus, OH, United States

Respiratory self-gated magnetization transfer (RSG-MT) sequence was developed and applied to abdominal organs to generate magnetization transfer ratio (MTR) maps during free breathing (FB) of patients. Results showed that respiratory motion artifacts were significantly reduced and high quality MTR maps were generated. Future studies will evaluate the application of these RSG FB MT techniques for the assessment of liver fibrosis and tumor desmoplasia in clinical settings.

Keywords

abdomen abdominal accurate acknowledge acquisition added adjacent alternative amplitude amplitudes another apparent application applications approaches approximate array artifacts assessment assumed audience authors avoid bandwidth bellows blue body breath breathe breathing calculating carried caudal clearly clinical coil collected combining commands commonly comply consent consistently coverage delay derived deterioration device diagnosis diagram dots duration effectively eliminate encoded encoding enrolled equation evaluate experiment expiration feasibility females fibrosis field foundation free frequency future gating generated gradient grant healthy holding inclusion informed institutional instructed intensity lead least length limit limited liver local magnetization males maps matrix medical motion next northwestern organs original overall patient patients permit pilot position potential principle prior proceeding providing pulse quality radiologists radiology readout reconstructed reconstruction recorded reduce repeated represent representative required requisite resolution respiratory saturation scanning segment segmented selected selective self seven severely slice slices software solutions spatial spinal studies sufficient target though threshold transfer typical useful view volunteer volunteers wish