Meeting Banner
Abstract #4164

Fat Confounds the Observed Apparent Diffusion Coefficient in Patients with Hepatic Steatosis

Jan Hansmann1, 2, Diego Hernando3, 4, Scott B. Reeder, 45

1Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, BW, Germany; 2Radiology, University of Wisconsin , Madison, WI, United States; 3Radiology, University of Wisconsin-Madison, Madison, WI, United States; 4Medical Physics, University of Wisconsin, Madison, WI, United States; 5Radiology, University of Wisconsin, Madison, WI, United States

The observed decrease in ADC in patients with fatty liver is, at least in part, artifactual due to residual fat signal near the water peak.

Keywords

absence account accurate addition although apparent approximately assess audience avoid become care cautiously clinical clinicians close coefficient collectively confidence confounded confounding confounds conjunction contain content control coordinates correct correction correlation decrease density dependence developed diffusion disease distinct distinguished errors even excitation excite fatty field fraction hepatic increasing inhomogeneities institute intercept interval introduce inverse investigated investigating least linear liver lobe localization localized localizer location magnetization maps measured medical medicine misinterpretation mitigate model must needed nuclear part patients peak peaks physics placement presence pronounced proton pulses radiology reason reeder relationship removes researchers schematic several slope spectroscopy spectrum statistical statistically strengths students suppression taken target theoretical tissue uncorrected underwent warranted water whether