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Abstract #4040

Glutamate, GABA and NAAG in Medicated Patients with Obsessive-Compulsive Disorder

Mona A. Mohamed1, Nicolaas A. J. Puts1, James Robert Brasic2, Manuel O. Uy3, Jarunee Intrapiromkul1, Gerald Nestadt4, Richard Anthony Edward Edden5, Peter B. Barker5

1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD, United States; 2Radiology, Johns Hopkins Medical Institutions, Baltimore, MD, United States; 3Applied Physics Laboratory, JHU, Laurel, MD, United States; 4Psychiatry, Johns Hopkins Medical Institutions, Baltimore, MD, United States; 5The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States

Through magnetic resonance spectroscopy (MRS) editing technique for GABA, NAA and NAAG, our findings suggests that there is no significant differences found in these brain metabolites concentrations in the anterior cingulate cortex (ACC) or the basal ganglia/thalamus (BG/TH) regions of OCD patients as compared to controls.

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Keywords

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