A Relationship Between Hyperpolarized 13C Pyruvate Metabolism and Tumour Volume in a Chronic Study of Oral Dichloroacetate Treatment of P22 Bearing BDIX Rat

Keywords

academic accepted acute adjusted administered administering administration animal animals apparent arterial automated bearing behind blocking bluff buffer buffered cancer cardiovascular cells chronic circulation coil comparing cone considerable control coronal correlations course curve curves days decreases delivery diameter diameters disrupts dissolved distances divided dosing drinking drugs electric examine excised explained female femoral final fisher fitted fixed flux function grant grow grows growth heating histology increasing indicate influences injection input integral kinetic kingdom lactate linear maintained male males markers measured mechanisms metabolic metabolism metabolite methodology modeling monitored necrosis necrotic needs nose oral oxidative paper particular peak period placed plays plotted positioned precursor product production pulse radiology rats reached received recent rectal relationship remote respiration response role sarcoma scanned scanning selection several slice slopes solution south spectroscopic staining statistical statistically strong student studies subcutaneously surface system tang temperature thick tissue transplanted transported treated treatment treatments trend tumor tumors understanding unpaired versus volume volumes water