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Abstract #3579

White Matter Abnormalities in Male Violent Offenders with Schizophrenia: A Diffusion Tensor Imaging Study Using Tract-Based Spatial Statistics

Yi Liao1, Lizhou Chen1, Xinyu Hu1, Junmei Hu2, Xuanli Chen3, Jianmei Liu2, Danlin Shen2, Qiyong Gong1, Xiaoqi Huang1

1Huaxi MR Research Center, Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China; 2School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, Sichuan, China; 3Computer Aided Medical Procedures & Augmented Reality, Technische Universitt Mnchen,, Garching bei Mnchen, Bayern, Germany

The purpose of this study is to perform a tentative study on schizophrenia patients with severely violence behavior to explore the microstructure abnormalities in the brain. Voxelwise statistical analysis of the FA data was carried out using Tract Based Spatial Statistics. The correlation between extracted FA value in specific regions and WCST, PANSS scores were evaluated for clinical explanations.

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Keywords

abnormalities according accurate advertisement aggression aided appraised articles audience augmented basic behavior bilateral body brain butler card carried causes cerebral characterized china clinical cluster computer connectivity controls corpus correct corrected correlate correlated correlation correlations costly diffusion dimensions disorder disruption dysfunction employing enhancement enough error errors evidence evidences exacted executive exhibited explore field flirt forensic fractional free function general generated gong good handedness healthy homicide human important index individuals inferior inspection integrity library longitudinal male many maps matched matrix medical medicine modified moreover neuropsychiatric nonlinear occipital offenders opinion overt oxford parametric participants past patients play positive problem procedures program psychiatry radiology reality recruited reduction reductions registered registration repetition reveal revealed risk role scale scales scanner schizophrenia school science score scores several severe shot significance slice social software sorting spatial statistical statistics structural studies subgroup suffering support syndrome table target template tensor though threshold tract various view violence violent visual white widespread years