Meeting Banner
Abstract #3557

The Dynamically Changing Default-Mode Network Functional Connectivity After Concussion in Sports

David C. Zhu1, Randy Pearson1, Jeffrey Monroe1, Sally Nogle1, Scarlett Doyle1, Doozie Russell1, Christine Liszewski1, Albert Aniskiewicz1, Michael Shingles1, Douglas Dietzel1, Michael Andary1, J. Kevin DeMarco1, David Kaufman1

1Michigan State University, East Lansing, MI, United States

Resting-state fMRI (rs-fMRI) was applied to understand the dynamics of functional connectivity of the default-mode network and other networks after concussion. It is still unclear if a dynamic recovery process as shown by rs-fMRI is still occurring even after neuropsychological tests return to normal. However, our pilot data clearly demonstrate that rs-fMRI can potentially serve as an important and sensitive tool to monitor the dynamically changing brain function after sports related concussion, and to further our understanding of brain alteration not revealed by neuropsychological and conventional clinical imaging techniques.

Keywords

abnormality activity acute alteration analyses anatomical appeared applied assessment athletes athletic audience axial brain cerebral changing clinical clinically clinicians closed cluster cognitive collected collection competition completed components concussed concussion confounder connected connection connections connectivity consistent controls corrections correlation correlations cortex cortices course courses datasets days default defined diagnosed diagnosis diffusion distant done dynamic dynamically east every examination eyes fiber fifth five fluid function functional furthermore general global impact implies included individual injury intercollegiate junction lateral linear lobe matrix medial mild mode modeled monitor monitoring motion network networks neuron nuisance occipital occurring often opposite overall physician pilot post process quadratic randy recent recovery recruited reduction reductions related relax removed resolution resting returned reveal revealed sally scores seed seeds serve shingles since slice slices sores sounding spinal sports still strongest subject subjects summarized sustained system table target template temporal threshold tool tracks traumatic trend trends unclear understanding union variables visual warped white whole