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Abstract #3540

The Effect of the Selection of Measured Tissue and Assumed Constant T1 Values on the Measurement of T1rho in Patients with Minimal and Severe Osteoarthritis (OA) at 3.0T MR System

In Chan Song1, Hyeonjin Kim1, Hye Jin Yoo1, Ja-Young Choi1, Sung Hwan Hong1

1Radiology, Seoul National University Hospital, Seoul, Korea

The purpose of this study was to evaluate the effect of the selection of measured tissue and assumed constant T1 values on the measurement of T1rho using 3D-gradient echo-based T1rho-weighted imaging sequence in patients with minimal and severe osteoarthritis (OA) at 3.0T MR system. The severity of cartilage degeneration was shown to have larger effect on T1rho from the assumed constant value to the measured tissue values in T1 value at the femoral cartilage at 3.0T. Therefore the usage of measured tissue T1 when T1rho is measured should be taken into consideration for the precise diagnosis of cartilage pathphysiology or the multi-center comparative study irrespective of the selection T1 value.

Keywords

able abnormal absolute addition affected although articular assumed assumption background biochemical blockade bone bottom cartilage cartilages caused classified clinical coil color comparative compartment compartments conditions consideration constant construct constructed currently damaged decreased degeneration degree dependence developed diagnosis distribution early equation error evaluate evaluated even except excluded expected experience fact female femoral fitting five flash grades gradient hong human improved in vivo increasingly instead intensity investigators irrespective knee know known largely larger least lengths link literatures lock longer make male management manual mapping maps materials matrix measured measuring middle mild minimal minutes national neglected nonlinear ones osteoarthritis parallel pathological patient patients percent pixel pixels precise preliminary problems procedure programs pulse radiologist radiology real reported reports representatively score segmented selected selection sensitive severe severity slice slices solutions song space spin squares stages subjects sung symptoms system table taken technical tendency thought tissue took trio usage usages useful variable variation varying view visual whole years young