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Abstract #3434

Comparison of R2* Measurements Values and Reproducibility in Liver Metastases and Normal Liver

Nina Tunariu1, 2, David John Collins1, James A. d'Arcy3, Veronica A. Morgan4, Sharon L. Giles4, Catherine J. Simpkin4, Timothy A. Yap5, Nandita M. De Souza6

1CR-UK and EPSRC Cancer Imaging Centre , Institute of Cancer Research & The Royal Marsden Hospital, Sutton, London, United Kingdom; 2Drug Development Unit, Institute of Cancer Research & The Royal Marsden Hospital, Sutton, London, United Kingdom; 3CR-UK and EPSRC Cancer Imaging Centre, The Institute of Cancer Research, Sutton, London, United Kingdom; 4CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research & The Royal Marsden Hospital, Sutton, London, United Kingdom; 5Section of Medicine, Institute of Cancer Research & The Royal Marsden Hospital, Sutton, London, United Kingdom; 6CR-UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, London, United Kingdom

Intrinsic susceptibility weighted (ISW) MRI and derived R2*measurements have been described as potential tool for tumour hypoxia assessment in prostate and breast cancer. The aim of this study was to measure R2* in normal liver and in liver metastases, compare these measurements and establish their reproducibility.

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