Meeting Banner
Abstract #3422

Early Detection of Response to Radiotherapy in Brain Metastases Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Chen-Hao Wu1, 2, Chuan-Han Chen1, Yi-Ying Wu1, Jyh-Wen Chai, Clayton Chi-Cheng Chen, Chung-Ming Chen2, Wen-Yih Isaac Tseng2, 3

1Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan; 2Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 3Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan

Early assessment of metastatic brain tumor response to radiotherapy is vital for treatment optimization for the individual cancer patient. The purpose of this study was to assess the performance of DCE, a novel MRI protocol for apoptosis, as a tool for the early detection of response of brain metastases to radiation therapy.

Keywords

absolute acquisition administered adults assess assessment automated available barrier basis biomedical biomedicine bird blood body bolus brain broken cage cancer cerebral close coefficient coil college common completely condition contrast correlate correlates cover decrease defined detection diagnostic dose dynamic early enables engineering enhanced entire flush functionally general generated gradient head help hospital implemented important indicated injection injector institute intravenously leakage lesions maps materials matrix measure medical medicine metastases ming modality national occur optoelectronic outcome particularly passage patient patients perfusion permeability permits post power predict prediction previous proven quadrature quantification quantitative question radiation radiology radiotherapy raises recalled recurrence referred regional reliably required resection resolution response role saline sensitive series sessions slice slices software solitary sonata spoiled stable steps studied studies sufficient suggested suitable susceptibility systems technology temporal therapeutic therapy trans transfer treated treatment tumor tumors underwent vascular veterans whereas whether