Monitoring Temporally Selective LDH-A Gene Deletion in Prostate Cancer Using Hyperpolarized Frequency Specific 13C-MRI

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acknowledgments activity adjacent administered administering administration allowed already anatomical anesthetized animal appreciable appropriate assessment award beth biomedical bottom cancer carbon catheter chemical circumscribed classical clearly coil coils combination complete conducted confirm consistent constructs containing controlled course date days deaconess decline decrease decreased define defined deleted deletion detected determine develop diffusion dissolution done equipped eventual every evident expression findings frequency gene generated genetic gradients grant grew identification in vivo indicate initial initiated initiation injected injecting injection instrument instruments introduced john knockdown knocked known lactate larger lesion longer male measured measures medicine meeting metabolism mice micro mixture model models monitor monitoring mouse occur oxford oxygen part period placed polarized poster preliminary previous production progression proof prostate protocols proton pulses radiology reduction resolution respectively respiration response scanner selective selectively several shimming short slice spontaneous studied studies substantially suggested system tail temperature temporally tissue tramp treatment trigger tumor tumors underway underwent variety varying vertical volume week wide