Meeting Banner
Abstract #3403

31P MR Spectroscopic Imaging of Patients with Prostate Cancer at 7T

Miriam W. Lagemaat1, Eline K. Vos1, Marnix C. Maas1, Thiele Kobus1, Andreas K. Bitz2, 3, Mark J. van Uden1, Stephan Orzada2, 3, Arend Heerschap1, Tom W.J. Scheenen1, 2

1Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; 2Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany; 3Diagnostic and Interventional Radiology, University Hospital Essen, Essen, Germany

The potential of 31P MRSI to detect prostate cancer in vivo at 7T was investigated in 12 patients with or suspected of having prostate cancer. The metabolites ratios PE/γATP, PE/tPLM and Pi/yATP showed significant difference between prostate cancer and normal prostate tissue. The performance of 31P MRSI to detect prostate cancer may improve further by increases in spatial resolution.

Abstract PDF Presentation Video

Keywords

abundant accomplish account accumulation acquisition adiabatic aggressiveness agreement amplitudes apex assessment become body calculating cancer caused channel choline chosen citrate clinical clinically coherence coil complex compound considerable considered containing content corrected corrections decrease decreased detect detected detection diagnostic discarded elevated elevation energy enhanced example except expresses extraction fits fitting fluid grade healthy human in vivo individual induced inorganic inspected intensity investigated largely limits local mainly major many maximize median medical metabolite metabolites might minutes moreover muscle nearly obscured optimize original overlap partial patient patients peaks performance phosphate potential precise prevented probably profile prostate proton pulse pulses quantitative radiological radiology rather recorded reflect reflects related relevant reliable report reported resolution respect respectively rigid safety samples saturating score selected selection seminal separate several shimming significantly since smooth space spatial spectra spectroscopic spectroscopy spins strength studied studies suggesting suspected system table taken tissue transition transversal tumor tumors ultra unaffected usually versus visually vitro volume whole zone