Meeting Banner
Abstract #3025

Multispectral Fusion-Based Detection of Virchow-Robin Spaces

Vikas Kotari1, Vasiliki N. Ikonomidou2

1Electrical Engineering, George Mason University, Fairfax, VA, United States; 2Bioengineering, George Mason University, Fairfax, VA, United States

Virchow-Robin spaces are perivascular structures whose dilation can be a biomarker of microvascular disease, vascular dementia, hypertension etc; therefore their detection and characterization may prove useful for disease monitoring. In this study, we present a novel automatic detection technique for VRS detection based on multispectral fusion of information derived from a combination of MPRAGE and T2 weighted images. The approach minimizes noise-driven false positives, resulting in high sensitivity and specificity. The technique is fast and fully automated, making it appropriate for routine use.

Abstract PDF Presentation Video

Keywords

acquisition additionally administered aged aging allows appear applied arterioles assess automated automatic automatically award bioengineering blurring brain clinical coil combined common commonwealth comparing component contained count counting cylindrical defined dementia depleted detect detected detection dilation disease diseases dots electrical engineering false fast filter filtered final fluid fully fund fused fusion generated growing head healthy hyper hypertension hypo illustrate illustrates improves inclusive individual infarcts informed intense intensities intervention isolate isolated isolates journal lesions like machine manual manually marked mask masks mason median medical minimal minimize native negatives neurological neurologically neurology noise observer original overlaid part peaks performance place positives predominantly processing project proposed providing recognized registered registration related represent represents requires resolution respectively robin scanner sclerosis sensitivity shape significance since smith space spaces specificity stability step structures subject subsequently suggested supported surround table take threshold trained transactions transform true truth underwent useful user usually utilizing vascular veins vision volunteer volunteers white years