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Abstract #3007

Atypical Sulcal Patterns in Pre-Readers and Beginning Readers with a Familial Risk for Developmental Dyslexia

Kiho Im1, Nora M. Raschle1, Jennifer Zuk1, Jennifer Minas2, Ola Ozranov-Palchik1, Nadine Gaab1, Patricia Ellen Grant3

1Boston Children's Hospital, Harvard Medical School, Boston, MA, United States; 2Massachusetts Institute of Technology, Cambridge, MA, United States; 3Boston Children's Hospital, Boston, MA, United States

Developmental dyslexia (DD) is one of the most prominent specific learning disabilities, affecting 5-17% of children. The goal of this study was to investigate possible structural pre-markers of DD in pre-readers as well as beginning readers using sulcal pattern analysis.

Keywords

abnormalities adults allows already alterations arrangement atypical automatically basin basins battery beginning behavioral bilateral birth brain brains catchment characterized child childhood children clinical closely computed computer control corresponds cortex cortical date decoding deepest degree dependent depth detected determine develop development developmental diagnosis difficulties disabilities distribution dyslexia early edge examine examined experience exploited familial family feature features fluent function functional genetic geometric give goal grade graph graphs hemispheres hospital hypothesis hypothesized identification implications individual institute international language learning least lobe lobes long longitudinal match matched matching matrix measure measured medical member naming natl node nodes onset optimal parietal paths pattern patterning patterns performance phonological pipeline pits poor position press prior proceedings processing prominent quantitatively readers reading recognition related relatively risk school sets significantly similarities similarity skills spectral spelling standardized start structural structure studies substantial suggests surface surfaces tasks technology temporal third topography topology typical utilized variable vision watershed whether white whole word