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Abstract #2952

Coordinated Anatomical Growth of Motor, Sensory, and Visual Networks in Early Infancy

Weili Lin1, Wei Gao1, Feng Shi1, Li Wang1, Gang Li1, Jingxin Nie1, Hongtu Zhu1, Dinggang Shen1

1Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

It has been suggested that brain regions with similar functions may exhibit a similar growth trajectory, also known as coordinated brain growth. Using gray and white matter volume and cortical thickness growth trajectories during the first 18mons of life through a longitudinal imaging study of normal pediatric subjects, brain structural networks of motor, sensory and visual functions were discerned. Results are consistent with the known brain regions possessing these functions. The existence of coordinated brain anatomical growth in early infancy may offer an invaluable tool to explore maturation processes of higher order brain functional networks during early brain development.

Keywords

acquisition addition allowing alone anatomical appears approaches attentional bias biomedical brain central channel chapel closest coil combined combining comparing completed comprehension consistent coordinated correction correlation cortical dedicated deforming descriptions detailed development diffuse discerning early employed every evidently exhibited exhibits expected explore finding fink fisher focal frontal function functional functions gray growth guided head healthy hill hypotheses identified implying importantly improve inclusion incorporating individual infancy infant inner integration interaction jointly known lack life lobe localized longitudinal mapping matrices measures motion motor natural networks neuron north note offer outer panel parallel physics pipeline possess post potential press primary processed quantitative rage rather reconstructed reconstruction recruited regional registered related reported reveal revealing reveals reviews scanned segmentation sensory separately sets severe short shorten since skull sleep specifically specificity speech starting stripping structural subject subjects superior surface surfaces tasks template temporal threshold tissue together trajectories trajectory transformed undergo understood unique visual volumes volumetric whereas white whole