1H MRS Reveals Decreased Motor Cortex Glutathione in Patients with ALS

Keywords

abundant accomplished according affected allowing alternate alternated alternatively antioxidant applied array assessed brain briefly cell channel clinically coil college component compounds confirmed consistent cortex cortical covariate criteria cross decreased defense deficiency deficit derived desired detection diagnosed direct disorder documented domain dominant doublet edited editing either elevating eliminated enrolled evidence excitations exploring expressed familial finding fitted fitting flanked forms frequency glutamate gradients head healthy hemisphere implementing implicated important in vivo inadequate incorporating independent inhibiting interleaved inversion investigate knowledge lacking lactate lateral matched measure measured medical metabolite metabolites models modulated monitoring motor much neurology noninvasive normality objectives observational opposite overlapping oxidative pair pathology patients peak physicians placement potential press prior protons pulse pulses radiology recorded response reveals role sample sclerosis secondary sectional selective significantly signs simultaneously singlet spectra spectral spin spoiler sporadic strategies stress stronger studies subjects subtracting suggesting supporting surgeons survival system therapeutic tissue treatment unsuppressed viability volume volunteers warranted water yielded