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Abstract #2796

First in vivo Imaging of the Mouse Brain at 4.7 T Using a Subcentimeter HTS Surface Coil

Simon Auguste Lambert1, Marie Poirier-Quinot1, Ludovic De Rochefort2, Jean-christophe Ginefri2, Luc Darrasse1

1UMR 8081, IR4M, Univ Paris Sud, CNRS,, Orsay, Paris, France; 2UMR 8081, IR4M, Univ Paris-Sud, Orsay, Paris, France

For field strengths of 4.7 T and above, cryocooled probes based on normal coil conductors at 30 K have been commercially developed and afford SNR gain factors of 2-4. Only few studies relate sensitivity improvement using superconducting coil above 3 T. A particularly challenging issue with HTS coils for in vivo applications at high field is the design of sub-centimeter coils in order to achieve SNR gains overcoming the limits of normal conducting cryocooled probes. This is the first report of in vivo imaging using a subcentimeter cryocooled HTS 6 mm mean diameter surface coil at 4.7 T.

Keywords

absence according accounting achieve acquisition adjusted allowed anatomical anesthesia application applications assuming available bandwidth benefit black body brain challenging channel characterization clinical coil coils combined commercially complete concern conducting conductive conductivity copper coupled cryostat decreased decreasing dedicated design determine device diameter diluted displayed encountered enough equivalent estimations evaluated expected expressed features field fields filters finally frequency function gain gains geometry good gradient granting highly identical immediately impedance implementation improve improved in vivo induced inductively infinite injection investigated issue laboratory limited limits load loaded local losses made magnitude mainly matrix measured mice mode model mouse nitrogen noise nude observe ones operated optimal optimized overcoming particularly perspectives phantom phantoms poor preliminary probes problem quality rapidly reach receive receiver relate related report resolutions resonator respectively response rest room sample samples semi sensitivity sets sites sources spatial spectrum step strengths stronger studies superconducting surface switch table temperature temperatures thank theoretical transmit turn typical unit univ unloaded yield