CEST Effect at 2ppm (CEST@2ppm): A Potential Biomarker for Grading Brain Tumor Malignancy

Keywords

according acquisition addition advantageous affected agent aggressive amide among amplitude animal animals approved assigned assistance authors bioengineering biomedical biomedicine brain brains cancer cells central chemical clinical committee concentration concentrations considered consistent constrained continuous contrast contrasts contribute contribution contributions corrected correlates critical decrease decreases detected differently direct energy evaluate even exchangeable exchanging fast feasible field fine fisher fitting five flash fluxes functions grading growth head health helps hence indicating individualized initials institutes institutional integral intra journal localized located loosely major malignancies malignancy mapping maps medicine metabolically metabolites might model models national necessary nonlinear normalized nuclear outcome patterns peak peaks physiological pickup pixel planning plays potential predict previous progresses project protocol proton protons pulse quantitative rats readout reduced regulation respectively respiration rest role round saturation scanned scanner shot significantly slice slow spectra spectral spectroscopy spectrum stage summed system technical tends tentatively tissue transfer treatment tumor tumors unit validated vary visible water wave width