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Abstract #2488

Longitudinal Investigation of Diffuse Hemorrhagic Lesions Using Using Quantitative Susceptibility Mapping (QSM)

Andreas Petrovic1, Ferdinand Schweser2, Andreas Deistung3, Eva Scheurer1, Jrgen R. Reichenbach2

1Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; 2Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital Friedrich Schiller University Jena, Jena, Germany; 3Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

Dating of hemorrhage is important in clinical and forensic medicine. In this study we measured the susceptibility of artificially created hematomas in 6 volunteers at different times to investigate if susceptibility changes due to changes of the oxygenation state of hemoglobin could be used. Quantitative susceptibility mapping is a unique method to measure magnetic susceptibility in vivo. The suspected increase of magnetic susceptibility could not be observed. This could be caused by blood being already fully deoxygenated at the time of the first measurement. Additionally, confounding factors as an increase of the hematocrit and recurring fat during resorption influence the measured susceptibility values.

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