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Abstract #2426

Magnetic Resonance Elastography of the Upper Airways with Guided Pressure Waves

Pascal Hagot1, Emeline Lamain2, Tom Doel3, Xavier Matre1, Redouane Fodil4, Luc Darrasse1

1IR4M(UMR8081), Univ Paris-Sud, CNRS, Orsay, France; 2Service de Neuroradiologie, Univ Paris-Sud, Hpital Bictre, Le Kremlin-Bictre, France; 3Oxford University Computing Laboratory, Univ of Oxford, Oxford, United Kingdom, United Kingdom; 4IRMB, Univ Paris XII, INSERM (U955), Creteil, France

Localisation of collapses in the upper airways of patients woth obstructive sleep apnea syndrome is a critical issue to guide and individualize the potential surgical option and procedures. Acoustic measurements may provide valuable information on the upper airway conformation and allow discrimination of healthy and pathological region. Mean amplitudes per slice ranged between 13 and 42 μm along the anterior-posterior direction, 11 and 43 μm along the feet-head direction, 11 and 47 μm along the right-left direction. The generated pressure wave is efficiently guided through the upper airways from the mouth down to the end of the trachea.

Keywords

achieved acoustic airway airways allow amplitude anatomical anatomy anterior appear around array awake basic cartilages cavity central characterize characterized clearly coil collapses collapsing comfort complexity component computing conformation critical cycle despite determined discrimination displacement distribution drawn dynamic efficiently elastic element esophageal exam expected favors feet fields gathered generated gradients guard guide guided guiding head healthy hence human identical individualize influence insights invasive inversion issue kingdom laboratory largely latter light like limited local long loss loudspeaker manually maps materials mechanical medical missing moduli modulus monitoring mouth mouthpiece muscles muscular natural normally onto options oscillatory oxford paths patient patients pattern penetration pharynx practically pressure probed propagating propagation properties reached reflected regional scanner sense sensitivity sensitizing service shear silicon sleep slice snapshots spin spine structural structured structures subject supine surgical surrounding systems table taken technically thick throughout thyroid tissue tongue tube unique univ upper uvula valuable various vibrating viscoelastic viscous wave wavelength waves whole