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Abstract #2332

Applying MRI for Investigating Brain Plasticity Resulting from Attention Training on Healthy Highly Educated Subjects

Bob Hou1, A Smith2, J. Wiener2, J. Chong2, Julie Brefczynski-Lewis1, D Kerr2, D. G. McLaren3, Marc W. Haut2

1Radiology, WVU, Morgantown, WV, United States; 2Behavioral Medicine & Psychiatry, WVU, Morgantown, WV, United States; 3MGH, Harvard University, Cambridge, MA, United States

Attention training (AT) results in changes in brain structure, grey matter and the connections of the structures (i.e., brain plasticity). Here we present our study on applying resting state functional MRI (rfMRI), DTI, and high resolution structural images to examine the impact of AT on brain plasticity of healthy highly educated subjects. Our hypothesis was that brain plasticity including functional and structural connectivity and grey matter volumes results from AT within 2 weeks. Our results of rfMRI, DTI, and tensor based morphometry (TBM) on the AT of the healthy highly educated subjects demonstrated the brain plasticity indeed happened within 2 weeks.

Keywords

ability among analyses anisotropy applied applying asked attention axial back behavioral bilateral biomedicine brain brains close coil completion component computer connections connectivity control controls coordinates corpus cortices coupled covering days default deviation deviations done dorsal drawn dynamical educated education eloquent enhanced enhancements enhances equal even examine executive eyes females field form fractional frontal functional functions gray happened head healthy highly human hypothesis implies improvement increasing increment indeed independent indicated individual intrinsic investigating known lead lewis linkage listed longitudinal look males mapping maps matched materials matrix medicine memory minutes modalities mode nature network networks occipital parametric participants plasticity practice prior programs psychiatry pulse radiology receive recruited regional related reported resolution respectively rest resting rows scanned scanner score scores shape significantly slice slices smith spatial statistical strength structural structure structures subject subjects suggested system table tail tasks though training trainings twice variance versus view vision volume volumes wager weeks whole wiener years yellow