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Abstract #2299

Isoflurane Supplement Prevents Epileptic Activity in fMRI Studies Under Medetomidine Anesthesia

Xiaopeng Zong1, Mitsuhiro Fukuda1, Alberto Vazquez1, Seong-Gi Kim1

1Department of Radiology, University of Pittsburgh, Pittsburgh, PA, United States

 

Keywords

acquisition active activity administration alpha although amplitude anesthesia animals apparent approximately arrow arrowheads arrows arterial arteries artery audience bars became become becomes block blood bold bolus capture cerebral coil column combination concomitant conditions consistent consisting constrictions constricts continuous coronal cortical courses covering decrease delivered dependent diameter diameters dilations dose drugs earlier elapsed elicited epileptic evoked fast field fifteen flow forelimb frequencies frequency function functional generation gray heads hours illuminated importantly indicate indicates indicative induced induces infusion initial injected injection known larger laser local longer made male marked matrix measured measuring minutes mitigated neural normalized observation open optical oscillations oxygenation periods placed popular pressure prevents primary prone pseudo randomized rats reached recorded recording representative researchers response responses robust sampling scale sedative seem slightly slower soon started still stimulation studied studies suggest suggested supplement supplemental supplementary supplementing suppressed surface surgery system target traces turned twenty unclear unit vein veins venous vessel vessels window