DSC-MRI Derived T2* Leakage Effect Depends on Structural Features of Extravascular Space

Keywords

additional apply assuming audience basic blood bolus brain brown cell cells cellular clinically clinicians cluster clustered clustering clusters coefficient compact compartmentalization compartments complex computed computing concentration concentrations considered contrast contribution corresponds created creates currently decreases density dependence dependent depends derived disordered distance distributed distribution distributions dominated ellipsoids evaluate example extra extracellular extract features field finding finite fixed flow fold fractal fraction fractions gradient highly increasing index indicated indicates induced influence injection inter intra intracellular investigate investigation island jerry keeping leakage long magnitude mathematical medical metrics minutes molecular network observation pass passes patients peak penetrate percent perturbation phantoms phys potentially presence properties proposed providence radii random randomly ranging recently recovery relationship respective respectively response school science sciences sensitivity separation several simulated slope south space spatial specifically structural structure structures studies substantially suggests susceptibility taken target termed tissue together transverse treatment tree tumor tumors typical underlying variation variations varied vascular versus volume yields