Bolus Tracking Perfusion Imaging in Humans Using Quantitative Arterial Input Function

Keywords

acquisition adjustment agent although animals applicability applicable arise arterial arteries artery audience background behavior blood blue bolus brain calculation capillaries cardiac carotid characteristics clinical coefficients comprising concentration confocal content contrast convolving correct correction cortex derived determination determined diffusible dimensional direct discuss discussed dispersion dose error evaluating evaluation excited expected explained exploits feasibility finite flow fold fraction framework frequency function general goes good gradient gray histograms hospital human humans induced inflow input internal introduced inversion known laser literature local long male maps mater measured measuring median microscopy might model necessary neck note numerous operation output overall patient patients peak perfusion poor porcine projection proposed quantification quantified quantitative rather reasonable recently recovery regime regularization related reported resolution section segmentation series shape since site slice slices slight smaller statistical studies suggest suits table target temporal terms theoretically theory thing tracer tracers tracking transport tree typical typically unambiguously unrealistically vascular verification vessels volume white whole