The Influence of Vascular Morphology on DSC-MRI Derived Blood Volume Measurements in Brain Tumors

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abnormal abnormally actual affect agent agrees alter anti apply arbitrary arterial assumption audience averaging basic bifurcation blood brain branching calibration cancer central cerebral characterize clinical clinicians closely compartmentalization computational compute computed concentration constant contrast course courses create created currently curve daughter decrease decreased degree dependence derived diameters dose encouraging example exceptionally exists explore features featuring field finite fractal fraction fractions gradients greater herein heterogeneity heterogeneous highly identifying in vivo increasing index induced influence institute introduced introducing investigate junction latter length like linear little marked measured model morphological morphology narrow need needed network networks node note occurred patients patterns possessed predominant preliminary previously properties random ranging relationship replicate reported representing response science scientists segment segments serial serially shaped simulate simulated smaller spatially starting structural structure structures studies substantial suggest suggesting summarized susceptibility symmetric target tended termed tissue transverse treatment tree trees tumor tumors types uniform validate variability variation vascular vessel vessels volume whereas wider