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Abstract #2152

Silent Pseudo-Continuous Arterial Spin Labeling

Michael Helle1, Tim Nielsen1

1Philips Research Laboratories, Hamburg, Germany

Conventional pseudo-continuous arterial spin labeling (pCASL) employs trapezoidal gradient waveforms and requires high gradient strengths in combination with high slew rates for sufficient labeling of flowing blood spins, which results in mechanical vibrations and a high acoustic noise level. In this study, possibilities are presented on how to reduce the acoustic noise level and the mechanical strain of a pCASL sequence, either by optimizing the labeling interval duration or by applying a sinusoidal gradient waveform for the labeling sequence or both.

Keywords

acoustic acoustical adapting adjusting allows altered amplification amplitude amplitudes apart applying approaches arterial avoids background black blood cause certain changing characterization clinical coil coincides combination comfort comparable completely complicated components constant contains continuous contribute control corresponds costs counteract decrease decreased delay deposited deposition detailed directly dramatically duration efficiencies efficiency efficiently either enables energy estimating even expected expense experienced experiment extended favorable feeding field flowing frequencies frequency function fundamental gradient gradients green hardware harmonic harmonics healthy highest increasing instead intensity interval investigated kept labeling laboratories local loss major materials measure mechanical might modified noise optimized optimizing original overcome patient pattern possibilities post power preparatory problem prominent proposed pseudo pulse pulsed pulses ranging read recorded recording reduce reduced reduces reduction reflected requires respect scanner separated service shape sharp significantly silent sinusoidal slew slices solid spectrum spin strengths stress strong stronger sufficient synchronously technicians train transfer translate trapezoidal variations varying view waveform waveforms yielded