Evidence for the Improved Biological Interpretability of White Matter Connectivity Derived Following Tractogram Filtering Using SIFT

Keywords

acquisition alternative analyses appear applied applying approaches appropriate assessed atlas benefit biases biological biologically body brain clear closely compensate connecting connections connectivity constrained construction corpus corrected correlation cortical count counts dale deconvolution decreases define defined definition denoted density deviation diagonals diffusion dissection distortions enhanced evaluate evaluating even example expected fact filtering fraction framework frontal generated generating health hemisphere hemispheric heuristics histograms human improved incorporating induced inferred institute inter intra intrinsically inverse investigate isotropic known length lobe locally long longer make male match matrices matrix meaningful measure mental metric million mimic motion network networks node nodes optimal orientation pair particular pathways pipeline population predict prevalence processed produced properties proportion proportional proportionality proposed protocol qualitative qualitatively quantitative quantitatively reconstruction reconstructions reduce reflected relevant reported seeded seeding segmentation selectively sift smith spherical streamline streamlines structural subject suggests superficial susceptibility system table temporal threshold throughout track tracking unit volume volumes volunteer volunteers white whole wise