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Abstract #2075

Bipolar Single Spin Echo: Diffusion Encoding with Concomitant Field and Eddy Current Correction

R. Marc Lebel1, 2, Corey Allan Baron3, Christian Beaulieu3, Ek T. Tan4, Ajit Shankaranarayanan5

1GE Healthcare, Calgary, Alberta, Canada; 2Radiology , University of Calgary, Calgary, Alberta, Canada; 3Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada; 4GE Global Research, Niskayuna, NY, United States; 5GE Healthcare, Menlo Park, CA, United States

Diffusion imaging has become a crucial component of clinical and research protocols; robust and accurate diffusion encoding schemes are required to produce consistent and factual results. It was recently shown that the dual spin echo encoding scheme is prone to erroneous measurements due to concomitant fields, while the Stejskal-Tanner single spin echo encoding is susceptible to eddy currents. We present and validate an alternative encoding scheme, called bipolar single spin echo, which alleviates many of the problems encountered with current diffusion preparations.

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Keywords

accrual accurate advantages although amplitude amplitudes appropriate attenuated attenuation avoid avoided baron bias biomedical bipolar clinical coefficients cohort comparable compensation completely concomitant constant constants correct correction decreasing defined diffusion disadvantage distortions dual eddy emphasize encoding engineering ensure errors extending field fields global gradient gradients identical identified immediately immune important insensitivity lobe lobes minimize minimized modified necessary necessitates negative neglecting null nulled offers park partially polar power prevent prior proliferation prone propose proposed providing pulse radiology ramp readily readout recently reduce reduced refocusing reproducible residual robust scheme schemes selection sensitive sensitivity shorter shot side simulated site spatially spin studies substantially susceptible symmetric tanner tensor theory typical typically unbalanced variations various varying visibly