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Abstract #1843

Proof of Concept for Transrectal MRI-Guided Prostate Biopsies Using an Optically Referenced Targeting Device

Harald Busse1, Gregor Thrmer1, Josephin Otto1, Nikita Garnov1, Tim Riedel1, Arno Schmitgen2, Axel Winkel3, Thomas Kahn1, Michael Moche1

1Diagnostic and Interventional Radiology Department, Leipzig University Hospital, Leipzig, Saxony, Germany; 2Localite Biomedical Visualization Systems, Sankt Augustin, Germany; 3Invivo Germany, Schwerin, Germany

Prostate carcinoma (PCa) is one of the most common male cancers in the western world. While digital rectal examination, prostate-specific antigen (PSA) testing and transrectal ultrasound-guided biopsies are still the primary tools for prostate diagnostics, multiparametric MRI has an emerging role in both imaging diagnostics and procedural guidance. The purpose of this work is to present a virtual real-time navigation option for transrectal MRI-guided prostate biopsies, to estimate the targeting accuracy, and to report on the preliminary clinical experience.

Keywords

accuracy accurate accurately acknowledged adjusted aligned anterior approval assistance automatic axial axis basis biomedical biopsies biopsy board bore calibrate cancer cancers central clinical common complication complications components computes considered coordinates corrected corrections custom define detected deviation device devices diagnostic diagnostics dial dials digital documented established examination experience experimental fast feasible feedback feet findings five freedom fully gland glaze greatly guide guided helpful hours impaired implemented improve informed intervention interventions knobs localization made male marker markers materials meant median mild minor minutes model modifications motion navigation needle optical option original orthogonal passive patient patients phantom pitch placement planning plate position posterior previous procedural proof prostate prototype radiology rapidly real registration relatively reliable remaining report revealed rotation samples scanner scene screen severe side simply situation software space spaced specimens still sufficiently system systems table taken targeting technical technically tightly tongues tools tracks tumor typically unambiguously underwent updating vessel virtual visible visualization waterloo western