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Abstract #1814

Absolute MR Thermometry for Near-Field Monitoring During MR-HIFU Heating

Mie Kee Lam1, Martijn de Greef1, Lambertus W. Bartels

1Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

In the application of MR-guided High Intensity Focused Ultrasound (MR-HIFU) to organs in the abdomen, the near-field area is at risk of undesired heat accumulation. Therefore, there is a need for a temperature mapping technique that can visualize the cumulative near field heating effects of subsequent sonications. In this work we show the potential of using multi-gradient echo (mGE)-based absolute MR thermometry at the subcutaneous fat-muscle interface for the assessment of the thermal build-up in the near-field area.

Keywords

abdomen abdominal ability absolute accumulation accuracy allows although amplitude assessment beam build certain chem chemical clearly clinical close coefficient coil component consistently containing control correspondence cumulative dependent described detect directly dose duration electron elevation ended equal except excitation excluded expected experiment exponential extract extrapolating fiber field fitting focal frequency fresh gradient guided head heat heated heating highest illustrates in vivo include incorrect indicated initial inserted intensity interface investigations least lipid little local location made make mapping maps measured measures measuring medicine modeled molecular monitoring muscle near need nonlinear note observation optic organs oscillation outer overestimated patterns pelvis phys placed porcine positioned potential precise prior probably probe procedure process quantitative quantitatively receive representing retrieved risk sample scanned sciences screening seem simplification simulations slice slight slightly spatial spot square squares starting subcutaneous subject subsequent supported suppression system taken targeted temperature temperatures thermal thermometry tissue translational trust undesired unpublished validation verify visualize wall water whilst wise