Meeting Banner
Abstract #1482

19F Gas Flow Measurement of C3F7H During Constant Flow and High Frequency Oscillatory Ventilation

Janet Friedrich1, Daniel Feldmann2, Lars Krenkel2, Claus Wagner2, Laura Maria Schreiber1

1Department of Radiology, Johannes Gutenberg University Medical Center, Mainz, Germany; 2Institute of Aerodynamics and Flow Technology, German Aerospace Center, Gttingen, Germany

The aim of the current study is the development of MRI methods that enable the investigation of gas flow mechanisms during high frequency oscillatory ventilation. This work includes flow measurements during three constant flows (19.9, 30.6 and 41.4 L min-1) and the comparison to direct numerical simulations (DNS) using a second-order-acurate finite-volume method and to data measured with a volume flow meter. 19F-MRI, DNS and flow meter data are in good agreement. Flow measurements during HFOV of 4 Hz were successfully performed and velocity profiles could be recorded at different phases of the ventilation cycle.

Keywords

acquisition acrylic acute addition adumbrated aerodynamics aerosols aerospace agree airway airways align allow allowed already artificial attributed axial biomedical bulk care characterize coil colorless comparable completely complex component conditions confirm constant contrast correct critical cycle dependent determined development device diameters dimension direct distress eddies enable equations even exhibit expected finite flattened flow flows fluctuate fluorinated foundation frequencies frequency geometrical glass good gradient gradients help human includes institute integrating intensity introduced introduces investigation laura lung maria material measure measured measuring mechanics mechanisms medical medicine meter modified needed numerical optimized oscillating oscillation oscillatory overall overcome parallel patients pattern period phantoms pharmaceutical pipe pipes pixel possibility pressure profile profiles prolongs propellant protective radiology rapid reception reduce regime relatively resolution respectively respiratory sensitive simulated simulations slice smooth sonata space steep stokes straight strategies strategy subsequently substantially suppl syndrome system technology tidal trachea tracking transmission transport trigger turbulent understand utilizing velocity ventilation verifies volume widely wise