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Abstract #1431

Regional MRI Left Ventricular Ejection Fraction Compared to Wall Motion Scoring and Late Enhancement Scar Imaging

Avan Suinesiaputra1, Brett R. Cowan1, Pau Medrano-Gracia1, Daniel C. Lee2, Alistair A. Young1

1Anatomy with Radiology, The University of Auckland, Auckland, New Zealand; 2Feinberg Cardiovascular Research Institute, Northwestern University, Chicago, IL, United States

In this study, we calculated regional ejection fraction (EF) from a 4D left-ventricular mathematical model derived from cine MRI. We investigated the potential of using this to distinguish abnormal segments in ischaemic patients, which are currently clinically assessed by (regional) visual scoring. In general, regional EF is well correlated with visual wall motion scoring and late gadolinium enhancement. Normal regional EF varied between regions with the highest in (S6, S12, S16) and lowest in (S2, S3).

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Keywords

abnormal according anatomy apex apical artery assess automatic automatically axis basal became calculation cardiac cardiovascular challenge cine cohort common computed coordinate coronary correlates correlation decreased definition derived determine disease divided dysfunction dysfunctional dysfunctions ejection element enhancement except excluded expert female fems finite fraction function gadolinium generate global gold guide highest hypo indicates indicator infarct institute interpolation investigated late lateral long lowest made male mathematical middle mild model models moderate motion myocardial northwestern patients periodic progressively radiology recommendations regional regionally registered remains remote retrospectively scar scores scoring segment segmented segments several severe short significantly software spatially spline studied stunning sufficient suggesting system temporally unpaired unreliable useful varied varies ventricular version visual wall years young