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Abstract #1422

Comparison of Under-Sampled Cartesian Pulmonary Perfusion MRI Reconstructed with Either View Sharing or HYCR

Scott K. Nagle1, 2, Laura C. Bell3, Mark L. Schiebler1, Christopher J. Francois4, James H. Holmes5, Sean B. Fain, 12, Kang Wang5

1Radiology, University of Wisconsin, Madison, WI, United States; 2Medical Physics, University of Wisconsin, Madison, WI, United States; 3Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 4Radiology, University of Wisconsin-Madison, Madison, WI, United States; 5Global Applied Science Laboratory, GE Healthcare, Madison, WI, United States

Quantitative contrast-enhanced pulmonary perfusion MRI has been limited by the need for high temporal-spatial resolution, full-lung coverage, and the need to scan within a reasonable length breath-hold. The purpose of this work was to compare the performance of 3 different Cartesian under-sampling methods in combination with 2 alternative reconstruction methods to perform whole-chest, time-resolved pulmonary perfusion MRI with isotropic 4mm resolution and 0.5-1s temporal resolution. Qualitative assessment of image quality at peak parenchymal enhancement was comparable. However, quantitative assessment of the contrast enhancement curves showed higher maximum values, steeper up-slopes, and shorter rise-times using HYCR rather than view-sharing reconstruction.

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Keywords

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