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Abstract #1391

MR Quantification of Longitudinal and Circumferential Strain in Left and Right Ventricles Subjected to Patchy Microinfarct, Large Infarct and Combined Insult

Mohammed Suhail1, 2, Mark W. Wilson1, Steven W. Hetts1, Robert F. Mattrey3, Maythem Saeed1

1Department of Radiology, University of California San Francisco, San Francisco, CA, United States; 2School of Medicine, University of California San Diego, La Jolla, CA, United States; 3Department of Radiology, University of California San Diego, La Jolla, CA, United States

We aimed to quantify longitudinal and circumferential strain in the left and right ventricles in animals subjected to solely LAD microemboli or LAD occlusion/reperfusion with and without microemboli using cine and tagged MRI. This analysis shows that LAD occlusion/reperfusion with microemboli causes severe impairment in longitudinal and circumferential strain in the LV, while other interventions showed impairment in circumferential strain only. The interaction between right and left ventricles after ischemic interventions is clearly demonstrated by the compensatory increase in right ventricular free wall contraction.

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Keywords

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