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Abstract #1328

Valve Opening and Closing Kinematic Assessment in Patients with Aortic Stenosis

Julio Garcia1, Romain Capoulade2, Lyes Kadem3, Eric Larose2, Philippe Pibarot2

1Radiology, Northwestern University, Chicago, IL, United States; 2Laval University, Quebec, Canada; 3Concordia University, Montreal, Quebec, Canada

The analysis of aortic valve kinetics during systole could provide incremental prognostic information beyond what is obtained for the standard valve effective orifice area. The aims of this study were to measure aortic valve opening and closing kinetic by cardiovascular magnetic resonance and to examine their association with markers of poor prognosis in patients with aortic stenosis.

Keywords

according achieved acquisition addition adjustment adverse among annulus aorta aortic appears aspect assess assessment association asymptomatic avoid best beyond bicuspid blinded body chair characterize circulation clinical closing context control controls correlated correlates correlation criteria curve decreases determinants determine diastolic differentiate dimension effective eight ejection events examine examined excellent expressed favorably feasibility female findings flow formula fraction function geometry good gradient guidelines healthy heart identify improve included includes incremental instantaneous inter internal intra kinematic kinetic kinetics legend lester lyes markers matrix maximal might mild model morphology multivariate natural northwestern objectives observers opening optimally orifice outcomes panel parametric patients peak peptide period planning plasma poor powerful predict predictor predictors preserved prognosis prognostic proposed pseudo radiology reduced reduction related relationship reproducibility respectively risk score severe severity significantly slice slope spacing strong stronger studies subjects subset suggested supported surface systole systolic table temporal transform true underwent univariate upstream valve valvular variability variables velocity whole years