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Abstract #1232

Multi-Echo Susceptibility-Weighted Imaging with Adaptive Averaging

Chou-Ming Cheng1, 2, Hsiao-Wen Chung1, Hing-Chiu Chang3, 4, Tzu-Chen Yeh5, 6, Jen-Chuen Hsieh7, 8, Shing-Jong Lin7, Chao-Ying Wang9

1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University , New Taipei City, Taiwan, Taiwan; 2Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan; 3Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, New Taipei City, Taiwan, Taiwan; 4GE Healthcare, Global Applied Science Laboratory, Taipei, Taiwan; 5Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan; 6Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, Taiwan; 7Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan; 8Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, Taiwan; 9Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Taiwan

Susceptibility-weighted imaging (SWI) and susceptibility weighted angiography (SWAN) helps delineating hemorrhage and veins by incorporating phase information from long echo time (TE) signals and performing multiple echoes averaged, respectively. Since the averaging operation with signals from early echoes inevitably results in a dilution of T2* weighting, the signal-to-noise ratio (SNR) improvements and loss in contrast-to-noise ratio (CNR) present an obvious trade-off. In this research, an adaptive averaging scheme for multi-echo SWI is proposed, with weights of echoes adjusted according to the phase value of each voxel to achieve SNR improvements without sacrificing CNR.

Keywords

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