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Abstract #1221

High Resolution 3T MR Imaging of the Cochlea Using Composite Gradients and Intratympanic Gadolinium in an Animal Model

Travis A. Abele1, K. Craig Goodrich2, Seong-Eun Kim2, Gretchen Mae Oakley3, Joshua D. Kaggie2, J. Rock Hadley2, Dennis L. Parker2, Richard H. Wiggins III1, 3

1Radiology, University of Utah Health Sciences Center, Salt Lake City, UT, United States; 2UCAIR, University of Utah, Salt Lake City, UT, United States; 3Surgery, Division of Otolaryngology, University of Utah Health Sciences Center, Salt Lake City, UT, United States

High-resolution MRI is valuable for evaluation of the inner ear. Using a novel composite gradient system, operating at double gradient strength, we sought to demonstrate improved spatial resolution of the inner ear on 3T MRI. Deceased guinea pigs were imaged with 3D-CISS using the composite gradient system and conventional body gradients alone. 3D-FLASH after intratympanic gadolinium administration was performed with the composite gradients. Composite gradient CISS achieved 8-fold greater resolution with only 61% increased imaging time. 12 hour averaged FLASH images demonstrated the ultra-thin vestibular membrane of the cochlea. Potential clinical applications include better detection of endolymphatic hydrops and cholesteatomas.

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Keywords

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