Shifting Characteristics of Upper Motor Neuron Revealed by Voxel-Based Morphometry in Amyotrophic Lateral Sclerosis

Keywords

according acquisition affects affiliated assessments bilateral brain caused central characteristics characterized china clinical coil college concluded confirmed consequence consistent contiguous control controls corpus corrected correlation cortex cortical covariates criteria critical death deficits degeneration demeaned density detect detected deterioration determination diagnosis dimensional disease dominance efforts enough enrolled equipped especially evaluate explore failed fast foot frontal general gradient gray half hand head healthy hemisphere hospital impaired index inferior insular intense intensity involvement keep lateral life limb linear loss matched materials matrix medial middle ming minimal model motor neurology neuron neurons neurosurgery observation occurred occurs pathological patients predominant procedure process profound progressive proper proved psychiatry radiology reduced reduction reflected regional regionally regressed relationship remain remarkably representation respiration reveal revealed revised scanner sclerosis served seven slight spare speculated spoiled sporadic spread stages stationary statistical strategies striking studies subsequent superior support survive tend therapies therapy thought topography transmitted true twenty upper useful volume volunteers whole years