Reduced Diffusion and Perfusion in Bevacizumab-Induced Diffusion Restricted Necrosis Versus Brain Tumor Hypercellularity

Keywords

accurately acquisition adjacent administered advancing apparent attention atypical autopsy axial axially began best biophysics biopsy blood brain cancer cell chemotherapy clinical college conflicting considered consisted contained containing contrast coronal correlation counts created custom days decreased define demonstrating determine devoid diagnosed diffusion dose efficacy entire equivalent eventually express expresses expressing expression extensively extraction findings fixed formalin funding gadolinium gathered generated giving grade gradient healthier highest histological histology hypercellularity in vivo individually induced injection inst instruments manually maps mark matrix measured medical microscope middle motorized natl necrosis necrotic neighboring neoplastic nuclei orientation outline outlined overlaid patient perfusion peter photo photographed photos population portions post precisely previously prior process processed processing program radiation radiology rand recent recurrence registered relate reports resolution restricted reveal sample samples sampling segmentation segmentations segmented shot significantly slice sliced slices software stage stained standardized statistical stitched studied suggest surrounding suspicious taken together toolbox trans translational treatment tumor twelve type underwent versus white