Meeting Banner
Abstract #0834

Parcellation of the Cortex Using Restricted Diffusion Properties

Shani Ben Amitay1, Yaniv Assaf1

1Department of Neurobiology, Tel Aviv University, Tel Aviv, Israel

Parcellation of the cortex is traditionally achieved by visualization of the cortical cellular architecture. In this work we aim to segment the cortex into neuro-anatomical regions based on variations in restricted diffusion properties along the cortex. We use hierarchical cluster analysis (HCA) to segment the cortex based on DTI and CHARMED maps. HCA and surface based analysis of the restricted diffusion component (Fr) indicates that homologous regions share similar mean Fr values and that mean Fr differs among cortical regions. We find that CHARMED seems to be superior over DTI parameters for cortical characterization.

Keywords

according achieved addition advanced agreement aims allows although among amount anatomical applicability applying architecture axon basis bears boundary cellular characteristics characterization charmed cluster clustering clusters component computed consisting contrasts cortex cortical dale density depth diameter differ diffusion distribution establishing evaluated exhibit extracted extreme fibers fields fifth five fraction general generated good gray height hemisphere hemispheres hierarchical homologous include inconsistency index indicate indicated inner intermediate lateralization layers limited links maps matrix micro models moreover multitude natl neurobiology outer plotted powerful produce properties property protocol protocols providing randomly reflects related representative resolution respectively restricted sample sampled scanning seems segment share structural structures subject subjects suggest superior surface surfaces theoretically throughout tool traditionally tree underwent unified variance variations visualization volume white